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GHK-Cu upregulated the Nrf2/Keap1 pathway Nrf2 is attached to Keap1 in the cytoplasm under normal circumstances, while in the condition of stress, the stimuli of oxidative stress activate the separation of Nrf2 and Keap1 and translocate Nrf2 to the nucleus and switch on transcriptional activities (Figures 4A,C,D)

Le glutathion est un tripeptide naturellement produit par le foie, compos de trois acides amins : la cystine, l'acide glutamique et la glycine

After removal of clearly nonrelevant records based on title and abstract screening, approximately 40 to 70 studies were identified as potentially relevant to musculoskeletal biology, orthopaedic care, or perioperative considerations