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Description
NQO1, NAD(P)H dehydrogenase [quinone] 1
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Garrison DA, Talebi Z, Eisenmann ED, Sparreboom A, Baker SD (2020) Role of OATP1B1 and OATP1B3 in drug-drug interactions mediated by tyrosine kinase inhibitors
The proposed reason the combination is more than the sum of its parts is that amylin agonism appears to sensitize hypothalamic leptin signaling

In particular, Akt phosphorylation, compared to ERK phosphorylation, appeared to be more sensitive to the phosphorylation of Met, which is evident by the dramatic reduction in pAkt in the case without 51 (Fig

10.1021/tx9701687 20 ChengJ
