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Despite compelling preclinical data, human trials of prooxidants have been disappointing 7

Lipoic acid but not dihydrolipoic acid can react with specific sulfhydryl residues of Keap1, causing the release of Nrf2 (34)

After the percentage record of linear motile spermatozoa at 200 magnification under a phase contrast microscope in three different microscopic fields for each sample, the final motility ratio of frozen-thawed sperm motility in each group was calculated based on the mean of three successive estimations (55, 57)

Collectively, these approaches underscore the growing recognition of mitochondrial vulnerabilities as viable targets in CRC therapy

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