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Consult a qualified healthcare provider before starting any new supplement regimen
Finally, in a meta-analysis of randomized trials on the use of vitamin B supplements for homocysteine reduction, folate supplementation had no significant effect on the 5-year incidence of CHD

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B12 deficiency can affect individuals of all ages, but most particularly elderly individuals, as older adults are more likely to have decreased stomach acid production, which is necessary for B12 absorption and they easily develop vitamin B12 deficiency

human clinical trials are limited

I get asked about these every single week in clinic
