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Description
Rather, in a genetically sensitive population, such viruses and bacteria stimulate the patient's immune system to become "supercharged" and trigger an immunological final common pathway that ultimately results in injury to the medium-sized arteries of certain organs
Elevated cAMP subsequently triggers the expression of the microphthalmia-associated transcription factor (MITF), a key regulator gene believed to control melanocyte development, differentiation, and survival

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N, Nuclear (cataract)
Even small mismatches can add up over time

Qiao et al
