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A similar replenishment of GSH stores was observed in primary rat hepatocytes exposed to ethanol and pretreated with curcumin [170]

Current evidence suggests that FRDA pathogenesis creates a highly conducive environment for lipid peroxidation (Figure 1), driven by dysregulated iron handling, amino acid metabolic shifts, and the failure of both glutathione (GSH)-dependent and independent pathways [29,63]

Then, cells were sedimented by centrifugation (14,000 rpm, 5 min) and resuspended in 1 mL of fresh 50 mM potassium phosphate buffer to measure the fluorescence using a Varioskanr TM LUX Multimode Microplate Reader (Thermo Fisher Scientific, Massachusetts, MA, United States)

This complex is then directed to the lysosomes, degraded, and free B 12 is then transported into the cytosol (Figure 2) [28]

Cyclodextrin Hydrogels: rapid Removal of Aromatic Micropollutants and Adsorption Mechanisms

[DOI] [PMC free article] [PubMed] [Google Scholar] Pawar S
