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J Clin Oncol 2021 ASCO Annual Meeting 39(suppl

Hyperoxia exposure can harm mitochondrial activity in the lungs, resulting in ES and alveolar injury, activating the pulmonary unfolded protein response (UPR), and increasing UPR downstream effectors, in turn resulting in alveolar growth disorder (32)

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Environmentally sensitive traits, such as temperature-dependent sex determination (TSD) in reptiles and some amphibians, interact with genetic mechanisms

doi: 10.3390/nu7043011

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