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These evidences are crucial for optimizing current therapeutic strategies for preterm infants and ultimately enhancing their quality of life

After cell counting, the cells in each group were centrifuged at 210 x g for 5 min at 37C to remove the supernatant and then diluted in PBS to 5x106 cells/ml

Subsequently, the cells were treated with BPTES (3 M, a glutaminase inhibitor that blocks the glutamine oxidation pathway), etomoxir (4 M, a CPT1A inhibitor, which is crucial for the transport of long-chain FAs from cytosol into mitochondria for oxidation), or UK5099 (2 M, an inhibitor of the glucose oxidation pathway that blocks the mitochondrial pyruvate carrier) successively, and oxygen consumption rate (OCR) was measured prior to and after the addition of each inhibitor

The safety and efficacy of oral levocarnitine has not been evaluated in patients with renal insufficiency

Hudson & Tabet 2003 Cochrane Review: A Cochrane Review of 15 clinical trials (including 13 of those in the meta-analysis above) assessed 1 to 3 g/day ALCAR supplementation versus placebo over 12 to 52 weeks in participants with mild to moderate dementia or cognitive decline