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The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis

As an on-demand treatment, its duration of effect is limited, and it cannot replace long-term strategies such as L-DOPA-carbidopa intestinal gel or continuous subcutaneous apomorphine infusion, which aim to provide stable plasma drug concentrations

LL-37 induces mast cells to release IL-31, a cytokine associated with itch and inflammatory skin diseases

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Random genetic and/or physiological variations between horses may be a potential explanation for the findings, which is supported by wide standard errors of the means for most cytokines reported herein
