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GEP can be important in identifying these patients by comparing the GEP of MDS, de novo AML, and sAML

GPX4 presents with a typical thioredoxin motif containing four -helices that are localized near the protein surface, and seven b-strands, five of which cluster together forming a central b-sheet (see Figure 3 for a crystal structure representation of GPX4 adapted from the PDB (6ELW)) [50]

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Grandjean P, Landrigan PJ: Developmental neurotoxicity of industrial chemicals

Pain relievers will help reduce both of these side effects

doi: 10.1038/labinvest.2011.130 90 ZhangDD