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For commercial use please contact [email protected] Introduction Vitamin B12 (B12), or cobalamin, is a cobalt-containing compound, and exists in four forms, methylcobalamin (methyl-B12) and adenosylcobalamin (adenosyl-B12) that naturally occur in the body, and cyanocobalamin (cyano-B12) and hydroxocobalamin (hydroxo-B12) that are synthetic forms used in supplementation and food fortification