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Ophthalmologica 209(1):1113

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In addition, Irg1-deficient phagocytes, which cannot produce itaconate, have shown increased susceptibility to M.tb infection, with infected mice exhibiting higher bacterial loads, reduced survival, exacerbated inflammation, extensive necrotizing granuloma formation and elevated neutrophil infiltration in the lungs [104, 105]

Machado-VieiraRBaumannJWheeler-CastilloCLatovDHenterIDSalvadoreGet alThe timing of antidepressant effects: a comparison of diverse pharmacological and somatic treatments

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