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The pathogenesis of bullous morphea is unknown, but it is generally thought to be an autoimmune disorder, and treatment of coexistent ulcers can be challenging

However, current clinical research on MenSCs still faces limitations
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Transcriptomic analysis was used to examine the potential mechanisms, followed by both in vitro and in vivo validation of key protein expression levels in the ACSL4/ALOX15 signaling pathway

Among all ROS, OH is the most reactive species

Glutathione plays a critical role in reducing oxidative stress and supporting liver function, but levels can decline due to aging, stress, and environmental exposure