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Iron export is regulated by the specific ferrous iron exporter ferroportin 1 in the plasma membrane in conjunction with a multi-copper ferroxidase, such as ceruloplasmin

Riederer P, Sofic E, Rausch WD, Schmidt B, Reynolds GP, et al

doi:10.1080/09637486.2018.1547688 Visekruna I, Rumbak I, Samarin IR, Keser I, Ranilovic J

In their study, PBCA nanoparticles coated with polysorbate 80 (PS80) were able to successfully deliver dalargin, an antinociceptive peptide unable to cross the BBB by itself

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