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doi: 10.1093/nar/gkae973 Summary Keywords atheroscelrosis, cholesterol metabolism, acetyl-L-carnitine (ALC), SREBP2, HMGCR Citation Xing J, Du Z, Li F, Wang Y, Zhang Z, Gao X, Han L, Sun X, Sun H, Du Y, Hu C, Yu H and Qin Y (2024) Acetyl-L-carnitine ameliorates atherosclerosis in LDLR / mice by modulating cholesterol metabolism through SREBP2-dependent cholesterol biosynthesis

doi: 10.1101/gad.334219.119 122 ShanKFengNZhuDQuHFuGLiJet al

Abstract Regulation of body fat storage involves signalling between centres that regulate feeding in the brain and sites of fat storage and use in the body 1,2

iScience 27 , 108589 (2024)

Therefore, targeting T-cell metabolism or disrupting the metabolic balance between cytotoxic T cells and Treg cells may help enhance the antitumor immune response