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People with certain health issues should not take them

Naive T cells require three essential signals for activation: T cell receptor (or CD3) engagement, co-stimulatory receptors (such as CD28) activation, and cytokine stimulation (IL-2 for expansion)

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Quality control is primarily carried out using high-performance liquid chromatography (HPLC) for purity determination and mass spectrometry (MS) for identity confirmation

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