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Functional enrichment and network submodulation refined the focus to 43 proteins implicated in cancer pathways, namely, AKT1, APAF1, AR, BIRC7, BMP2, CASP3, CCNA2, CDK2, CDK6, CTNNA1, EGFR, ESR1, ESR2, F2, FGFR1, GSK3B, GSTA1, GSTA3, GSTM1, GSTM2, GSTP1, GSTT2B, HRAS, HSP90AA1, IGF1R, IL2, JAK2, JAK3, KIT, MAP2K1, MAPK8, MET, MMP9, NOS2, NQO1, PGF, PPARD, RARA, RARB, RXRA, RXRB, TGFBR1 and XIAP

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Una dosis preclnica tpica de 10 g/kg en rata equivale referencialmente a ~1.6 g/kg en humano (~110 g para 70 kg)

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