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For example, the prodrug and cancer chemotherapeutic agent irinotecan is a camptothecin analog that is bioactivated by plasma and intracellular carboxylesterases to SN-38 ( Figure 65 ), a potent inhibitor of topoisomerase 1

Circulating oxidative stress parameters in pre- and post-menopausal healthy women and in women suffering from breast cancer treated or not with neoadjuvant chemotherapy

Human-specific duplication and mosaic transcripts: the recent paralogous structure of chromosome 22

Garca-Villarreal L, Hernndez-Ortega A, Snchez-Monteagudo A, et al

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The patient has an initial BMI at or above the 95th percentile for age and sex (meeting criteria for obesity)