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Including doxorubicin in cyclodextrins can reduce the cardiac toxicity associated with this anticancer drug, protecting the heart without diminishing the effectiveness of the treatment

doi: 10.3389/fcimb.2021.657775 Received 24 January 2021 Accepted 11 May 2021 Published 03 June 2021 Volume 11 - 2021 Edited by Diego Luis Costa, University of So Paulo, Brazil Reviewed by Maria Regina DImprio Lima, University of So Paulo, Brazil

10.1111/j.1349-7006.2009.01386.x 206 OuY.WangS

14,15 Using isotope tracing techniques, scientists have gained insights into the transformation of metabolites within tumors, revealing that lactate is a direct carbon source for the TCA cycle

This suggests that Mito-Tempo is a potential treatment option for patients with advanced APAP poisoning

doi: 10.3390/molecules28217444 169 HwangB.ChoJ.HwangI