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For the result of PCD prevalence estimation by the Bayesian framework in other gnomAD populations, the prevalence is 1:1,134,461 (95% confidence interval: 1:2,300,3251:650,711) in African American (AFR) population, 1:148,320 (95% confidence interval: 1:314,1551:82,852) in admixed American (AMR) population, 1:921,025 (95% confidence interval: 1:28,837,5931:211,888) in ASJ population, 1:1,964,440 (95% confidence interval: 1:13,880,6671:645,273) in Finnish in Finland (FIN) population, 1:282,613 (95% confidence interval: 1:413,7091:202,688) in NFE population, 1:84,707 (95% confidence interval: 1:404,3291:31,975) in South Asian (SAS) population, and 1:16,375 (95% confidence interval: 1:41,4101:8,272) in East Asian (EAS) population (Figure 3B)

Sci Rep (2022) 12(1):11542

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Amphetamine exerts analogous, yet less pronounced, effects on serotonin via VMAT2 as on dopamine and norepinephrine [160,185]

Beyond this remodeling effect, berberine hydrochloride down-regulates the efflux-pump gene CDR1 , reducing fluconazole extrusion and further sensitizing resistant strains (Zhu et al., 2014)
