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doi: 10.1002/ijc.29914 153 Garza-GonzlezERosMBosques-PadillaFJFrancoisFChoIGonzlezGMet al

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When the lesion is located in the scrotum, orchiectomy, and testicular pouch ablation are performed, and when the foreskin is involved, penectomy associated with urethrostomy is recommended [159]

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Metformin users, common among type 2 diabetes patients who then add semaglutide, face a double hit since metformin independently reduces B12 absorption by 10-30% over long-term use