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In esophageal cancer, CD38 expression on myeloid-derived suppressor cells (MDSC) discriminates between MDSC with high and low immunosuppressive function on T cells [53]
Importantly, the effector cytokine production of the M38 316323 specific CD8 + T cells increased after CD38i treatment (Figure 8L and Supplemental Figure 8G)
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For this reason, we recommend ordering a month in advance of when you plan to start using it
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