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Because Vitamin B12 is essential for the protective sheath covering your nerves (myelin), a lack of it can cause nerves to misfire

They have previously been shown to modulate gating properties 37,38 and trafficking of iGluRs 24,39 or interactions with other synaptic proteins 40

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This is why research protocols typically use subcutaneous administration shortly before the intended sleep onset

Zheng S, Ge Y, Fang X, Liu M, Sun H, Deng X, et al

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