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But payers dont accept assumptionsthey want documented language

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Dysfunctional LSECs also produce profibrotic molecules, such as TGF-, which promote the activation of HSCs, thereby increasing ECM production and endothelial vasoconstriction in the hepatic sinusoids and accelerating the development of liver fibrosis (112)

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Long-term or indefinite use is common for sustained weight maintenance

Next Steps: A Collaborative Approach Patients are encouraged to discuss these findings in detail with their healthcare providers