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TMAO is known to activate the proinflammatory pathways and promote vascular inflammation and endothelial cell dysfunction through a variety of signaling pathways

doi: 10.1146/annurev-physiol-020518-114455 84 ChangAYLaliaAZJenkinsGDDuttaTCarterRESinghRJet al

It represents that the G protein (Olfr 78 and GPR41) produced by SCFA generated by GM can stimulate the release of GLP-1 and PYY, which can reduce blood pressure and inhibit atherosclerosis development

M.) 633647 (Elsevier, 2014)

Numerous studies have looked at the association between ascorbic acid intake and the risk of developing cardiovascular disease (CHD)
