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57,58 These patients had an increased concentration of the GSH degradative enzyme gamma-glutamyltranspeptidase in the SN, and a normal concentration of the synthetic enzyme gamma-glutamyl-cysteine synthetase

10.1007/s10661-019-7781-9 [DOI] [PubMed] [Google Scholar] Khan MU, Ahmad M, Khan MA, Afzal M (2022a) Linking microbial remediation with circular economy and sustainable agriculture: challenges and opportunities

Nutrition & Metabolism (2010) 7:52

Poor nutritional status is often associated with chronic alcoholism, and thus alcoholic patients with APAP-induced hepatotoxicity may fall victim to both decreased body GSH stores as well as enhancement of the CYP enzymatic activity

In four proof-of-concept clinical studies, RPL554 demonstrated bronchodilator and anti-inflammatory effects and was well tolerated