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They do this by slowing down the activity of bacterial cells, keeping them in a phase where they no longer multiply

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Pozzi V., Sartini D., Morganti S., et al

So, we recommend using SL vitamin B12 rather than oral and IM, especially in patients who do not tolerate IM injection and patients who need prolonged vitamin B12 supplementation, such as patients with long-term metformin use and patients with pernicious anemia or with gastro-duodenal resection [51,52,53,54]

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Regular nutritional assessment and supplementation are essential components of safe combined therapy