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We were the first to show in an early phase I trial that NAC inhibits dense and irreversible sickle RBC formation and restores glutathione levels toward normal in adolescents and young adults with SCD [127]

Environmental factors, stress, and aging also contribute to its decline

Everything in this section is extrapolation based on the mechanism of action and user-reported outcomes

This combined approach could extend the period during which patients have a good quality of life and slow the progression of disability

Additionally, it seeks to summarize potential avenues for future research, exploring various aspects of plant-pathogen interactions