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Similarly, solid lipid nanoparticles loaded with curcumin and turmerone were optimized using response surface methodology for topical delivery, resulting in enhanced stability, controlled release, and reduced irritation [149]
In humans, two enzymatic reactions are dependent on vitamin B 12 methylmalonyl coenzyme A mutase (MUT) reaction and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) reaction (Fig 2)
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Charles G Minard, Institute of Clinical and Translational Research
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The autosampler was set at 4C, and the injection volume was 10 l
