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Regulated cell death (RCD), also known as programmed cell death (PCD), has been widely reported to have numerous links to the progression and therapy of many types of human cancer

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Silencing of MT by short interfering RNA (siRNA) was published by Tarapore et al., who used phage Phi29 motor pRNA as a vehicle to carry siRNA specifically targeted to MT-2A mRNA in ovarian cancers (Tarapore et al., 2011), and by Lai et al., who reported that silencing of the MT-2A gene by siRNA induces entosis (a process involving the invasion of one cell into another, and internalized cells are either degraded by lysosomal enzymes or released) in adherent MCF-7 breast cancer cells (Lai et al., 2010)

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J Neuroimmunol (1987) 16:283302.10.1016/0165-5728(87)90082-8 79 MeinlEAloisiFErtlBWeberFde Waal MalefytRWekerleHet alMultiple sclerosis

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