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J Neurosci (2013) 33(23):9592600

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Nonetheless, in a small crossover study of 26 human diabetic patients, 4 weeks of ebselen treatment did not alter plasma levels of oxidative stress markers, such as GSH/GSSG, isoprostanes, and nitrotyrosine, compared to placebo treatment [82]

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Immunomodulatory therapies These interventions aim to restore immune tolerance, reduce autoimmune attack, or protect beta cells without direct genetic modification