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Rodriguez-Temporal D, Herrera L, Alcaide F, et al

As these transcriptional alterations suggest a reduction in hepatic fibrosis in response to lowering oxalate via AGXT overexpression, we next evaluated hepatic fibrosis through histopathological and immunofluorescence analyses coupled with biochemical verification

Given the increased expression of cysteine catabolic enzymes, such as cystathionine -synthase (CBS), cystathionine -lyase (CSE) and 3-MST in different cancer cell types, it is likely that their relevance for cancer development is shared between the production of H 2 S (detailed later in the article) and the accompanying generation of metabolites that constitute carbon sources

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Richards is the past Chief of Plastic Surgery at Johns Hopkins Suburban Hospital