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Description
As was noted for DNMT1 and PRMT3, sigmoidal dose-response curves and reliable estimates of IC50 values could not be obtained since no significant inhibition was observed at the tested NNMT inhibitor concentrations
Studies have shown that it is relatively safe with minor side effects, which may include temporary redness, itching or headache at the injection site
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According to one report, vitamin B12 combined with omega-3 fatty acids may help slow cognitive decline in patients with early-stage dementia
Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work
Results vary by individual and treatment adherence
