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Patients with pernicious anemia or others who cannot absorb B from food typically need lifelong B therapy, often on a monthly injection schedule

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Thats why some people benefit from taking both forms or using a supplement with hydroxocobalamin, which converts into both active types

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doi: 10.1073/pnas.1721115115

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Engstrom LD, Aranda R, Lee M, Tovar EA, Essenburg CJ, Madaj Z, et al

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The effect of vitamin B12 on mental health can worsen in people who naturally suffer from confusion, paranoia, or mental fogginess

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doi: 10.3390/MA12040641 123 Muoz-BonillaA.Fernndez-GarcaM

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