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[DOI] [PMC free article] [PubMed] [Google Scholar] 135.van Montfort RL, Congreve M, Tisi D, Carr R, Jhoti H

Melatonin is primarily metabolized in the liver, where it is first hydroxylated to 6-hydroxymelatonin by cytochrome P450 enzymes CYP1A1 and 1A2 enzymes

Interestingly, although EE suppressed MSTN equivalently to the extent as IGF-1 did, it did not affect MAFbx and MuRF1 genes at all (Fig

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