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Moreover, we identified cg1120622, located in the REV3L gene, encoding a DNA polymerase catalytic subunit

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Further analysis using mass spectrometry of plasma-treated platelet supernatant reveals the up-regulation of 16 proteins, which may be crucial for the coagulation-promoting process 17

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Risk factors such as hypertension and diabetes, especially in aging organisms, affect the activity of eNOS, resulting in eNOS uncoupling

It also identified the putative longevity factor klotho (KL) 23 , as well as multiple proteins with unknown functions including uromodulin (UMOD) and kidney associated antigen 1 (KAAG1), as important kidney aging proteins