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References Tsimikas S, Stroes ESG

Surprisingly, we found that P-cadherin retroviral transduction of MCF-7/AZ breast cancer cells (E-cadherin positive) did not produce striking changes in cell-cell aggregation, which suggested that P-cadherin does not shift the balance of aggregation established by the endogenous cadherin in this system [54]

Inactivation of CDKN2A frequently results from homozygous deletion, although it can also arise from a truncating mutation in an allele, followed by a loss of heterozygosity, often due to loss of part of chromosome 9

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