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After reaching 65/70 years of age, the circadian rhythm of melatonin secretion almost completely disappears. MELATONIN IN SLEEP DISORDERS Melatonin as a hormone regulating the day-night circadian rhythm and seasonal biorhythm also participates in the process of mood, sleep, and its quality

When their seminal research was published in *Cell* in March 2017, it introduced the first precision senolytic peptide capable of selectively eliminating senescent cells while sparing healthy tissue, opening unprecedented opportunities for studying aging mechanisms and developing research tools for age-related cellular dysfunction

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