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But similar to hepatitis B, TA-1 for hepatitis C has become obsolete in favor of direct antiviral agents.7 Acute and long COVID Though thymosin alpha-1 received its fair share of negative press during the height of the COVID-19 pandemic, when some on social media promoted it as an FDA-approved cure for the illness (its not), more recent evidence suggests it may be able to reduce the severity of acute COVID-19 infections.24 In a study from 2023, researchers found that, in the acute phase after SARS-CoV-2 infection or reinfection, TA-1 could reduce, through the modulation of [dendritic cells], the amount of proinflammatory cytokines produced by T cells and improve lymphocyte function.25 Additionally, some experts suggest that TA-1 may also be a potential treatment for post-acute sequelae of COVID-19, better known as long COVID or long-haul COVID. Researchers explain that the results of their 2023 ex vivo study showed TA-1 improved the restoration of an appropriate response in long COVID patients with a chronically altered immune response.26 More research is needed, though

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Mallajosyula V, Ganjavi C, Chakraborty S, McSween AM, Pavlovitch-Bedzyk AJ, Wilhelmy J, et al

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