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Marschisello S, Di Pino A, Scicali R, et al

HSP90 inhibitors such as ganetespib (STA-9090) and AUY922 have been extensively evaluated in oncology, 54,55 where they disrupt the stabilization of oncogenic client proteins

Despite these challenges, it has been demonstrated that combining different antioxidants can have a synergistic effect, and such formulations are becoming increasingly popular (66)

Curr Opin Genet Dev 7:7579 Bourne HR, Sanders DA, McCormick F (1991) The GTPase superfamily: conserved structure and molecular mechanism

Nrf2-and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition