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At Weeks 4, 8, 12 and 16, cheilitis, xerosis, and dryness of eyes and nose were less frequent in patients who received the concomitant omega-3 supplement, compared to those who received tretinoin alone

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Site of disease is a clear determinant of outcome and an important prognostic factor

elegans , is activated by Lcr35, suggesting that the probiotic strain acts by stimulating its host via DAF-16 but also by suppressing the virulence of the pathogen (90)