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A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)

Am J Clin Nutr 86: 1738-1744 Malaguarnera M, Vacante M, Avitabile T, Malaguarnera M, Cammalleri L, et al

mild abdominal discomfort, flatulence, and hiccups [15,21,75,76,98]

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and (2) acting as a molecular chaperone to larger molecules resulting in a change in the structure, molecular dynamics, and function of the larger molecule

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