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By using the passive and/or active strategies for BBB regulation and crossing in a controlled and non-invasive manner, various drug delivery systems are engineered to facilitate the brain-targeted delivery of specific therapeutics including small-molecule drugs, proteins, genes, and other biopharmaceutics
[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Xu Z, Xie Y, Mao Y, Huang J, Mei X, Song J, et al
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