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ghk-cu reconstitution protocol Guide: How to Mix Copper Peptide Safely GHK-Cu Dosage and Protocol: A
Description
Genomic studies indicate that GHK-Cu influences the expression of over 4,000 human genes, approximately 6% of the human genome, including genes involved in DNA repair, proteasome function, oxidative stress response, and anti-inflammatory pathways

The significance of this paper is not only to compare the three routes of administration but also to evaluate them and determine which route is the best to administrate the drug
Consider the math

The complexes were solubilized from membrane using detergent (1% (w/v) LMNG and 0.06% (w/v) CHS) for 1 h at 4 C
After the study, almost 70 -90 % of GHK-Cu had been retained in the patch in tested animals

Pharmacol., 97(7), 589599 (2019)