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As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

Getting a prescription for vitamin B12 injection means you need a doctors watch

Clinical Biochemistry 2014

As you get older, your body naturally produces less NAD+

Following oral administration, Drug A is 100 % absorbed but 40 % bioavailable, while Drug B is 80 % absorbed and 60 % bioavailable