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Rigorous monitoring is imperative throughout the medications administration, and, in the presence of adverse reactions, it is prudent to gradually reduce the infusion rate or temporarily suspend it until the untoward effects abate

Palpate the abdomen for hepatomegaly (enlarged liver) or splenomegaly (enlarged spleen), which may be present in severe cases

It was also noted by Hong et al

It is related to a deficiency of the vitamins B12 and B6

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Protocols are not interchangeable between them, which is one more reason a provider evaluates each compound individually rather than applying a generic chart