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Effects of oxidative stress on viral infections: an overview

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Importantly, proteolytic cleavage of SPARC (secreted protein acidic and rich in cysteine), a matricellular protein abundantly expressed at sites of vascular injury and tissue remodeling, generates GHK-containing fragments that promote endothelial cell proliferation and neovascularization

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However, during the chronic inflammation, the glial activation causes an increase of ROS production and other neurotoxic mediators, leading a neuronal damage [52]

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No established upper limit exists because excess b12 excretes through kidneys without causing harm

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Orthobiologics in meniscus pathology, in Regenerative medicine in sports and orthopaedics: a new approach

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E.El SayedI

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