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[4] Yuan, C., Chen, D., & Wang, S

In skeletal muscle the PEP can be used for pyruvate synthesis which can then be oxidized by the PDHc and the resultant acetyl-CoA can be oxidized by the TCA cycle providing reduced electron carriers for ATP synthesis

It is secreted by I-cells in the duodenal and small bowel mucosa in response to protein and fat, with its main effects on the liver, gallbladder, pancreas and, interestingly, central nervous system (CNS)

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