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A number of studies have investigated the influence of L-carnitine supplementation in cattle ( In ruminants, a number of regulatory mechanisms are involved in the maintenance of carnitine homeostasis ( The carnitine biosynthesis is, among other things ( in vitro findings by Rebouche et al

The ante-MMPBSA.py [72] module of AmberTools 14 was used to convert the original topology of the system, remove all the waters and ions, specify the Born radii as mbondi3 , and generate the corresponding topology file to be used in the MM/GBSA calculations

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The vast majority of these substances are of natural origin [3], not subject to prescription, and can usually be easily obtained in the form of food supplements or herbal extracts

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