kras mutation and glutathion Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase glutathione biosynthesis Research advances in the treatment

Do Carmo S, Hanzel CE, Jacobs ML, et al

Mitochondrial accumulation of APP and Abeta: Significance for Alzheimer disease pathogenesis

7 , e2105 (2013)

Combined therapy with L-thyroxine and L-triiodothyronine compared to L-thyroxine alone in the treatment of primary hypothyroidism

#OncologyPharmacy #PharmacistsCare #OncologyAwareness #ChemotherapySafety #ClinicalPharmacy To view or add a comment, sign in Catastrophic Cerebral Infarctions in a Pediatric Patient with ALL Due to Mucorales Infection - just published by Alexander Aldejohann The case illustrates the potentially fulminant nature of Mucorales infection in immunocompromised children and the ultimate lack of a provenly effective antifungal prophylaxis against these organisms

Together, these findings support a model in which OCTN1 acts as a context-sensitive regulator of the inflammatory-oxidative microenvironment, reflecting a dynamic balance between protective adaptation and pathological impairment, and providing a mechanistic view for its bidirectional regulation and potential as a therapeutic target